All services can be customized, contact our team to discuss.
Our Services
Quantitative Metabolic Analysis
Different analytical methods with relative quantification available for:
Common microbial nutrients, media components and waste products (*)
Central carbon metabolites (**)
Fatty acids
Untargeted and semi-targeted analysis available
Semi-targeted analysis covers over 650 metabolites with ready quantification mixes for > 100 metabolites
< 10 minute assay
Optimized for large cohorts of samples (> 5 000 samples) (***)
Specialized Analysis
Metabolic flux analysis measures the activity of intracellular pathways by tracing isotopically labeled nutrients through downstream pathways and identifies metabolic pathways that are inhibited/stimulated in disease states
Metabolic boundary flux measures Indirectly the activity of intracellular pathways by quantifying the consumption or production of metabolites in media
“The team at CMRF has helped accomplish over 200 of its partners’ major metabolic research goals. They inspire everyone in the detection of microbial nutrients.”
Additional Services:
Absolute Quantitative Analysis:
Metabolite extraction and tailored extraction protocols
de novo Method Development
Consulting on experimental design, data analysis, and interpretation
Short Chain Fatty Acid quantification
Bile Acid quantification
Targeted quantification of key biomarkers in biological samples